The short answer
Yes. Rebuilt or re-downloaded automatically when needed.
What is it?
Simulators keep generated system files here, mainly the dyld shared caches built for each runtime so simulated devices boot and launch apps faster. It is created by the CoreSimulator service and typically takes a few gigabytes.
What happens if you delete it?
The caches are rebuilt automatically the next time a simulator boots, which makes that first boot noticeably slower. No device or app data is stored here.
How to remove it properly
Quit Simulator and Xcode, then move ~/Library/Developer/CoreSimulator/Caches to the Trash with Finder’s Go › Go to Folder….
Quit the app that uses it, then move it to the Trash. Empty the Trash when you’re sure.
How MoreRoom helps
MoreRoom recognises this item, shows its real size and when it was last used, and labels it “Safe to remove”. In the free version you can move it to the Trash in one click, with Undo; Pro collects every safe item at once.
Frequently asked questions
Is it safe to delete CoreSimulator Caches on Mac?
Yes. Rebuilt or re-downloaded automatically when needed. The caches are rebuilt automatically the next time a simulator boots, which makes that first boot noticeably slower. No device or app data is stored here.
Will Simulator caches come back after I delete it?
Yes. The caches are rebuilt automatically the next time a simulator boots, which makes that first boot noticeably slower. No device or app data is stored here.
How do I remove Simulator caches properly?
Quit Simulator and Xcode, then move ~/Library/Developer/CoreSimulator/Caches to the Trash with Finder’s Go › Go to Folder….